Bipolar Disorder or Manic-depressive illness causes extreme shifts in mood, energy, and
functioning. Overly energized, disruptive, and reckless periods alternate
with periods of sadness, withdrawal, hopelessness, and other depressive
symptoms. Unlike normal mood states of happiness and sadness, symptoms of
manic-depressive illness can interfere with school performance, family
relationships, peer interactions, and other everyday activities. Although
manic-depressive illness typically emerges in late adolescence or early
adulthood, there is increasing evidence that the disorder also can begin
in childhood. According to one study, one percent of adolescents ages
14-18 were found to have met criteria for manic-depressive illness or
cyclothymia, a milder form of the illness, in their lifetime.
NIMH research efforts are attempting to clarify the diagnosis, course,
and treatment of manic-depressive illness in youth. Evidence suggests that
manic-depressive illness beginning in childhood or early adolescence may
be a different, possibly more severe form of the disorder than older
adolescent and adult-onset manic-depressive illness. When the illness
begins before or soon after puberty, it is often characterized by a
continuous, rapid-cycling, and mixed symptom state that may co-occur with
ADHD or other behavioral disorders, or may have features of these
disorders as initial symptoms. In contrast, later onset manic-depressive
illness appears to begin suddenly, often with a manic episode, and to have
a more episodic pattern with relatively stable periods between episodes.
Various treatments known to be effective in adults with
manic-depressive illness also may help relieve the symptoms in young
people. The essential treatment for this disorder is the use of
appropriate doses of mood stabilizing medications. The most typical is
lithium, known to be very effective in adults for controlling mania and
preventing recurrences of manic and depressive episodes. Research on the
effectiveness of this and other medications in children and adolescents
with manic-depressive illness is ongoing. In addition, studies are
investigating various forms of psychotherapy to complement medication
treatment for this illness in young people.
Information
provided by the National Institute of Mental Health